Wednesday, June 29, 2011

CRPS Clinical Trials Open as of June 2011



By open clinical trials, I mean that either recruitment has not yet begun or is ongoing.  The U.S. National Institutes of Health listings presently contain 17 such trials:

1.  The Effect of Vitamin C on Preventing Complex Regional Pain Syndrome (CRPS Type I) Following Ankle Fracture
ClinicalTrials.gov Identifier: NCT01338129
Location:  Rabin Medical Center, Petah Tikva, Israel

2.  Graded Exposure (GEXP) in Vivo Versus Physiotherapy in Complex Regional Pain Syndrome Type I (CRPS-I)
ClinicalTrials.gov Identifier: NCT00625976
Responsible Party: Dr. M. Goossens, Maastricht University, Maastricht, The Netherlands
 
3.  Pain Exposure Physical Therapy (PEPT) Versus CBO in Patients With Complex Regional Pain Syndrome Type I (CRPS-1) (PEPTOC)
ClinicalTrials.gov Identifier: NCT00817128
Study Sponsor: Radboud University, Nijmegen, The Netherlands 
 
4.  Study of Proteins Associated With Complex Regional Pain Syndrome
ClinicalTrials.gov Identifier:  NCT00033969
Location:  National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States, 20892
 
5.  Intravenous Immunoglobulins in Complex-regional Pain Syndrome (PAINLESS)
ClinicalTrials.gov Identifier:  NCT00949065
Responsible Party:  Franz Blaes, MD, Dept. of Neurology, Justus-Liebig-University, Am Steg 14, 35392 Giessen, Germany
franz.blaes@neuro.med.uni-giessen.de
 
6.  Neurotropin to Treat Chronic Neuropathic Pain
ClinicalTrials.gov Identifier: NCT00006289
Location:  National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States, 20892
Sponsor:  National Institute of Nursing Research

7.  Use of Compression Glove to Prevent Complications After Distal Radius Fractures: a Randomized Controlled Trial
ClinicalTrials.gov Identifier: NCT01118715
Responsible Party: Michael Shuler, MD, J&M Shuler, Inc.
706-424-8438

msimmss@hotmail.com

8.  Analysis of Photoplethysmographic Signal in Lumbar Sympathetic Block (park001)
ClinicalTrials.gov Identifier: NCT01134289
Location/Contact:  Department of Anesthesiology and Pain Medicine, Seoul National University Hospital,
Seoul, Republic of Korea, 110744
Soo Young Park, MD 82-2-2072-0881 soo02@snu.ac.kr

9.  Peer Mentorship: An Intervention To Promote Effective Pain Self-Management In Adolescents
ClinicalTrials.gov Identifier:  NCT01118988
Responsible Party:  Lonnie K. Zeltzer, MD/Professor, Director of UCLA Pediatric Pain Program, UCLA Department of Pediatrics
Contacts:  Lonnie K Zeltzer, MD 310-825-0731  LZeltzer@mednet.ucla.edu
Jennie CI Tsao, Ph.D.  310-825-0731  JTsao@mednet.ucla.edu

10. Evaluation and Diagnosis of People With Pain and Fatigue Syndromes
ClinicalTrials.gov Identifier:  NCT00677157
Sponsor:  National Institute of Nursing Research (NINR)
Contact: Patient Recruitment and Public Liaison Office (800) 411-1222  prpl@mail.cc.nih.gov

11.  Regional Anesthesia Military Battlefield Pain Outcomes Study (RAMBPOS)
ClinicalTrials.gov Identifier: NCT00431847
Contact: Yolanda S Williams, MPH
(215) 823-5800 ext 2774
yolanda.williams5@va.gov
Contact: Holly Luu, BA
(215) 823-5800 ext 6506
holly.luu@va.gov
Sponsored by the Dept of Ver
Principal Investigator:  Rollin McCulloch Gallagher, MD MPH, Pain Management Service
LOCATIONS:
Locations

United States, District of Columbia
Walter Reed Army Medical Center
Washington, District of Columbia, United States, 20307
Contact: Lt. Col. Chester C Buckenmaier III, MD 202-782-7652

United States, Maryland
National Naval Medical Center
Bethesda, Maryland, United States, 20889
Contact: LCDR Michael Kent, MD 202-782-0917

United States, Pennsylvania
Pain Management Service
Philadelphia, Pennsylvania, United States, 19104
Contact: Lynn A Watson (215) 823-5800 ext 6023 lynn.watson@va.gov
Contact: Yvette Roberts (215) 823-5800 ext 6020 yvette.roberts@va.gov
Principal Investigator: Rollin McCulloch Gallagher, MD MPH
Sub-Investigator: Joan S Thomas
Sub-Investigator: Holly Luu, BA
Sub-Investigator: Yolanda S Williams, MPH

United States, Texas
US Army Institute of Surgical Research/Brooke Army Medical Center
Fort Sam Houston, Texas, United States, 78234
Contact: Cpt. Laura McGhee, PhD 210-916-5482

12.  Susceptibility to Chronic Post-Traumatic Extremity Pain
ClinicalTrials.gov Identifier: NCT00672711
Contact: Cecile Pestano, RN
248-964-3440
cpestano@beaumont.edu
Contact: Nickole Carlson, RN
248-898-1907
NCarlson@beaumont.edu
Responsible Party:  Craig T. Hartrick,MD, William Beaumont Hospital (Royal Oak, Michigan)
Phone: 248-898-1907



13.  Efficacy of Etoricoxib on Peripheral Hyperalgesia 
ClinicalTrials.gov Identifier: NCT01088256
Responsible party/Contact: Dr. Christoph Maier  +49/234/3026366  christoph.maier@rub.de
Ruhr University of Bochum, Germany

14.  Adenosine Activity in Producing Venoarteriolar Reflexes
ClinicalTrials.gov Identifier: NCT01280071
Location: Tel-Aviv Sourasky Medical Center, Israel
Contact: Lior Dayan, MD
972504051014
liordayan.3105@gmail.com

15.  Transcranial Magnetic Stimulation (TMS) Effects on Pain Perception
ClinicalTrials.gov Identifier: NCT00349050
Responsible Party:  Jeffrey J. Borckardt, Ph.D., Associate Professor, Department of Psychiatry and Behavioral Sciences, Department of Anesthesiology and Perioperative Medicine, Medical University of South Carolina (Charleston)
(843)867-5142

borckard@musc.edu

16.  Dupuytren's Disease and Extracorporeal Shockwave Therapy (DupuyShock-2010)
ClinicalTrials.gov Identifier: NCT01184586
Location:  Hannover Medical School, Plastic, Hand and Reconstructive Surgery, Hannover, Germany, 30625

Contact: Karsten Knobloch, MD
0049511532 ext 8864
knobloch.karsten@mh-hannover.de

Contact: Marie Kuehn
0049511532 ext 8864
Marie.Kuehn@stud.mh-hannover.de

17.  Effects of Vaporized Marijuana on Neuropathic Pain
ClinicalTrials.gov Identifier: NCT01037088
Contact: Haylee E. Donaghe, MS

916-734-2935
hedonaghe@ucdavis.edu
Principal Investigator:  Barth L Wilsey, MD  University of California, Davis








2 comments:

  1. Great set of links. I'm particularly interested in the vitamin c for prevention. Professor Paul Zollinger first did a study on this in 2000. The possibilty of preventing CRPS isn't widly known although many orthopedic surgeons now recommend it. I had a wrist fracture in 1998. I wish I'd known. I'll put a link to this page and post on my blog.
    crps rsd a better life

    ReplyDelete
  2. Thanks for dropping by The Manor, Jeisea. I think that one day soon, orthopedic surgeons will be able to advise a fairly simple "Pre-op CRPS" protocol that will include cost-effective prevention like Vitamin C.

    Awareness about Vitamin C is on the rise. Zollinger advises, I think, 500 mg over at least 50 days... A small thing to do that might have big rewards.

    http://www.jbjs.org/article.aspx?Volume=89&page=1424 [Zollinger/wrist]

    http://www.ncbi.nlm.nih.gov/pubmed/19840748 [foot/ankle]

    Thanks for the link to your blog! I've added yours to my blog list, known around here as "Tangents (And Other Voices)."

    ReplyDelete

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