CRPS Clinical Trials

ClinicalTrials.gov is a great resource that I try to periodically peruse for hip and happening research activity around CRPS/RSD. The following trials are recruiting or are on the verge of recruitment.

There has been a flurry of visitation to this blog as people google and otherwise search for information about Laura Beckett, who underwent the ketamine coma protocol in Germany and has unfortunately encountered problems due to infection with MRSA -- something far too common these days in ICUs (and hospitals, in general) the world over. Please note Clinical Trial #6 below that is investigating outpatient delivery of intravenous ketamine -- there is considerable misinformation being passed around about treatment with ketamine. It has NOT been banned in the United States -- on the contrary, studies and treatments are ongoing, just not that which employs the 5-7 day coma. And *that* is NOT banned, either -- it is simply subject to the FDA ruling which does not allow coma treatments that last longer than 2 days.

1 Recruiting Autonomic Dysfunction and Spinal Cord Stimulation in Complex Regional Pain Syndrome
Condition: Complex Regional Pain Syndrome
Interventions: Device: Spinal Cord Stimulator;
Other: CRPS patients under treatment other than spinal cord stimulator

2 Recruiting Effect of Delta-9-Tetrahydrocannabinol on the Prevention of Chronic Pain in Patients With Acute CRPS (ETIC-Study)
Conditions: Complex Regional Pain Syndromes; CRPS
Intervention: Drug: Delta9-Tetrahydrocannabinol

3 Not yet recruiting Graded Exposure (GEXP) in Vivo Versus Physiotherapy in Complex Regional Pain Syndrome Type I (CRPS-I)
Condition: Complex Regional Pain Syndrome Type I
Interventions: Behavioral: Graded exposure in vivo; Behavioral: Physiotherapy

4 Recruiting Safety and Efficacy Study of Ethosuximide for the Treatment of Complex Regional Pain Syndrome (CRPS) Type I Condition: Complex Regional Pain Syndrome, Type I
Interventions: Drug: Placebo; Drug: Ethosuximide

5 Not yet recruiting Pain Exposure Physical Therapy (PEPT) Versus CBO in Patients With Complex Regional Pain Syndrome Type I (CRPS-1)
Condition: Complex Regional Pain Syndrome, Type I
Interventions: Procedure: PEPT;
Procedure: CBO standard

6 Recruiting Double Blind Placebo Controlled Study of Outpatient Intravenous Ketamine for the Treatment of CRPS
Condition: Complex Regional Pain Syndrome
Interventions: Drug: Ketamine; Other: IV NSS; Other: Normal Saline

7 Recruiting Association Between Focal Dystonia and Complex Regional Pain Syndrome Conditions: Focal Dystonia; Peripheral Nervous System Disease
Intervention:

8 Not yet recruiting The Effect of Transcranial Direct Current Stimulation (t-DCS) On the P300 Component of Event-Related Potentials in Patients With Chronic Neuropathic Pain Due To CRPS or Diabetic Neuropathy
Conditions: Diabetic Neuropathies; Complex Regional Pain Syndrome Type II
Intervention: Device: TDCS/sham procedure on five consecutive days

9 Recruiting A Study of the Effect of Lenalidamide on Complex Regional Pain Syndrome Type 1 Condition: Complex Regional Pain Syndrome, Type 1
Intervention: Drug: Lenalidamide

10 Recruiting Evoked Fields After Median and Ulnar Stimulation
Condition: Complex Regional Pain Syndromes
Intervention: Procedure: Evoked fields before and after a local block (Xylocaine)

11 Recruiting The Efficacy of Motor Cortex Stimulation for Pain Control
Conditions: Neuropathic Pain; Phantom Limb Pain; Stump Pain; Brachial Plexus Avulsion; Deafferentation Pain; Facial Pain; Complex Regional Pain Syndrome
Intervention: Device: motor cortex stimulation

12 Recruiting Neurotropin to Treat Chronic Neuropathic Pain
Conditions: Causalgia; Reflex Sympathetic Dystrophy
Intervention: Drug: Neurotropin

13 Recruiting Evaluation and Diagnosis of People With Pain and Fatigue Syndromes
Conditions: Fatigue; Fibromyalgia; Pain; Complex Regional Pain Syndrome; Reflex Sympathetic Dystrophy
Intervention:

14 Recruiting Regional Anesthesia Military Battlefield Pain Outcomes Study
Conditions: Anxiety Disorders; Complex Regional Pain Syndrome Type II; Depressive Disorders; Post-Traumatic Stress Disorder; Substance Abuse
Intervention: Procedure: Regional Anesthesia

15 Recruiting Susceptibility to Chronic Post-Traumatic Extremity Pain
Condition: Chronic Pain
Intervention:

NOT APPLICABLE 16 Recruiting Effect of an Educational Intervention on Cardiac Patients' Participation Rate in Cardiac Rehabilitation Programs
Condition: Coronary Artery Disease
Intervention: Behavioral: Increasing awareness to importance and availability of CRP

NOT APPLICABLE 17 Recruiting Growth Hormone Secretagogue MK-677 Therapy Effect on IGF-1 Levels in CKD and ESRD Patients Conditions: Chronic Kidney Disease; End Stage Renal Disease
Intervention: Drug: MK-677

18 Recruiting Cerebrospinal Fluid Repository
Conditions: Amyotrophic Lateral Sclerosis; Cerebrospinal Fluid; Neurodegenerative Disease; Motor Neuron Disease
Intervention: